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Oxycodone hydrochloride 40 mg = Oxycodone base 36 mg Oxycodone hydrochloride 30 mg = Oxycodone base 27 mg Oxycodone hydrochloride 20 mg = Oxycodone base 18 mg Oxycodone hydrochloride 15 mg = Oxycodone base 13.5 mg Oxycodone hydrochloride 10 mg = Oxycodone base 9 mg Maximum daily dose: Oxycodone (base) ER capsules: 288 mg as the safety of the excipients has not been established maximum dose of oxycodone hydrochloride tablets has not been establishedĮQUIVALENCE OF OXYCODONE HYDROCHLORIDE TO OXYCODONE BASE: MAINTENANCE: Adjust dose every 1 to 2 days as needed to obtain an appropriate balance between pain management and opioid-related adverse reactions goal should be to find the lowest effective dosage for the shortest duration consistent with individual patient treatment goals Oral solution: To avoid dosing errors total dose should be included in both mg and mL Initial dose for OPIOID-NAIVE patients: 5 to 15 mg orally every 4 to 6 hours on an around-the-clock basis Oxycodone (base) ER capsules: 9 mg orally every 12 hours with food Oxycodone hydrochloride ER tablets: 10 mg orally every 12 hours Initial dose for OPIOID-NAIVE and OPIOID NON-TOLERANT patients: Use: For the management of acute pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate Usual Adult Dose for Chronic PainĦ0 and 80 mg extended-release (ER) tablets, a single dose greater than 40 mg (36 mg oxycodone base), a total daily dose greater than 80 mg (72 mg oxycodone base), or use of the 100 mg/5 mL (20 mg/mL) oral solution should be restricted to use in opioid-tolerant patients only Monitor patients closely for respiratory depression within the first 24 to 72 hours of initiating therapy and following any increase in dose. Because of the risks of addiction, abuse and misuse, the lowest effective dose for the shortest duration consistent with individual patient treatment goals should be used. Doses should be individually titrated to provide adequate analgesia while minimizing adverse reactions. Oral solution: To avoid dosing errors include total dose in mg and mLĬONVERSION from Other Oral Opioids: There is great inter-patient variability in the potency of opioid drugs and their formulations when converting patients to this drug from other opioids or when switching from controlled-release products, it is best to underestimate the oxycodone requirement and provide rescue medication than to overestimate and manage an overdose.
#WHAT PAIN MEDS CAN BE TAKEN 7 DAYS BEFORE HIP REPLACEMENT SERIES#
The following dosing recommendations can only be considered suggested approaches to what is actually a series of clinical decisions over timeĪs First Opioid Analgesic: 5 to 15 mg orally every 4 to 6 hours